Apixaban indications set to AMPLIFY?
نویسندگان
چکیده
منابع مشابه
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متن کاملCorrigendum: apixaban for the treatment of Japanese subjects with acute venous thromboembolism (AMPLIFY-J Study).
BACKGROUND Anticoagulation is recommended as standard of care for venous thromboembolism (VTE) (pulmonary embolism [PE]/deep vein thrombosis [DVT]), for which unfractionated heparin (UFH) and warfarin are used in Japan. In the multi-regional AMPLIFY study, a fixed-dose regimen of apixaban alone was non-inferior to conventional therapy for treatment of PE/DVT and was associated with significantl...
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disease have resulted in a greater number of deaths attributed to PE in recent years in Japan.2 Whereas the early diagnosis and treatment of VTE can result in relatively good outcome, PE is a fatal disease characterized by a high rate of mortality; indeed, sudden death may be the presenting symptom of VTE.3 Early diagnosis and early treatment, including inhibition of DVT progression and prevent...
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Direct oral anticoagulants (DOACs) are being increasingly used in the clinical setting for patients at risk of venous thromboembolism (VTE) and/or stroke. These medications offer valued benefits for long-term use, including a fast onset of anticoagulation, fixed anticoagulation profile (and consequent prescription of specified doses) and no requirement for routine monitoring. Apixaban is a sele...
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ژورنال
عنوان ژورنال: Nature Reviews Cardiology
سال: 2013
ISSN: 1759-5002,1759-5010
DOI: 10.1038/nrcardio.2013.106